Education Degrees

Degrees

MD; Medicine; Carol Davila University of Medicine (2001)

Residencies

Internal Medicine; The Christ Hospital (2009)

Fellowships

Hematology; Johns Hopkins University School of Medicine (2013)

Research & Publications

Clinical Trial Keywords

  • Leukemia, Bone Marrow Transplant, Hematologic Malignancies, Natural Killer Cells

Selected Publications

  • Ghiaur G, Yegnasubramanian S, Perkins B, Gucwa J, Gerber J, and Jones RJ. Regulation of Hematopoietic Stem Cell Self-Renewal by the Microenvironment’s Control of Retinoic Acid Signaling. PNAS, 2013, Oct1; 110(40):16121-6. Epub 2013 Sep 16. PMID: 24043786. PMCID: PMC3791732
  • Alonso S, Hernandez D, Chang YT, Gocke CD, McCray M, Varadhan R, Matsui WH, Jones RJ, Ghiaur G. Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance. J Clin Invest. 2016 Dec 1;126(12):4460-4468. doi: 10.1172/JCI88152 PMID: 27775549
  • Ghiaur G, Levis M. Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment. Hematol Oncol Clin North Am. 2017 Aug;31(4):681-692. doi: 10.1016/j.hoc.2017.04.005. Epub 2017 May 18. Review. PubMed PMID: 28673395; PubMed Central PMCID: PMC5512588.
  • Su M, Chang YT, Hernandez D, Jones RJ, Ghiaur G. Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment. J Cell Mol Med. 2019 Jun;23(6):4111-4117. doi: 10.1111/jcmm.14298. Epub 2019 Mar 28. PubMed PMID: 30920135; PubMed Central PMCID: PMC6533513
  • Hernandez D, Palau L, Norsworthy K, Anders NM, Alonso S, Su M, Petkovich M, Chandraratna R, Rudek MA, Smith BD, Jones RJ, Ghiaur G. Overcoming microenvironment-mediated protection from ATRA using CYP26-resistant retinoids. Leukemia. 2020 Mar 9;. doi: 10.1038/s41375-020-0790-4. [Epub ahead of print] PubMed PMID: 32152463.